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Metabolism: This merchandise is usually a metabolite of tramadol. Tramadol is metabolized within the liver via the enzyme CYP2D6 to variety O-DSMT. This metabolite has an extended 50 %-lifestyle than tramadol, leading to prolonged outcomes.Flipping the route of the R2 and R1 bonds brings about the R- and S- enantiomers of O-Desmethyltramadol. O-DMS